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Regenexx SCP (PRP)

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Henry Stiene, M.D. of Beacon Orthopaedics is thrilled to be the only physician (excluding spine) licensed in the TriState area to perform and treat patients with the Regenexx™ Family of Advanced Regenerative Medicine Procedures which include concentrated PRP and Regenexx Stem Cell Treatments.

Regenexx is the leader in orthopedic Regenerative Medicine in terms of research, tracking patient outcomes, presentations, and publications. For these reasons, Dr. Stiene chose to align with the Regenexx family to best serve his patients.

To contact Dr. Stiene about Regenexx please call (513) 389-3641


PRP is an emerging treatment in the field of Regenerative Orthopaedics. It has been in use in Europe for many years and Beacon was one of the first centers in the Midwest to utilize this treatment having performed over 2000 treatments since 2007. PRP is basically an acceleration of the body’s healing and regenerative powers.

Platelets are particles found in the blood whose primary purpose is to respond to injury and begin the healing process. They migrate to the site of injury and when exposed to injured tissue and release proteins into the bloodstream called growth factors. Growth factors recruit the body’s repair cells to the area of injury and these repair cells are known as stem cells. A stem cell doesn’t know what it is supposed to become until a growth factor signals it to become bone, ligament, tendon, muscle, or other tissues.

These types of stem cells are called mesenchymal stem cells and are recruited from the bone marrow and adipose (fat) tissue. Growth factors also recruit stem cells called hematopoietic stem cells that create new blood vessels. Tissue cannot heal or repair itself if there is no blood flow which allows oxygen and nutrients to reach the site of injury and to remove waste from the injured site. This is much like a construction site. The stems cells are the workers that will build the new tissue, the PRP is the subcontractors directing the workers, and the bloodstream is the route by which the materials get to the site to build and repair.

Components of connective tissue such as tendons and ligaments have a very poor blood supply and once injured can be very difficult to heal. A tendon is made up of thousands of individual fibers called collagen and bundle together very neatly and orderly much like the fibers or wires in an electrical cable. When a tendon becomes injured because of overuse or injury, the body tries to repair the individual fibers and because of poor blood supply growth factors and stem cells can’t do their job correctly and fibers are repaired with poorly organized tissue commonly called scar tissue.

Scar tissue does not have the same strength and elasticity as healthy tissue so when the same force, overuse, or trauma is placed upon the tissue containing scar, it fails, more tissue tears, more scar tissue develops and a vicious cycle of pain and dysfunction occur called tendinopathy. Tendinopathy is a very difficult problem to treat and treatments to date aim at relieving pain and restoring function, but the injured tissue remains. As a result, recurrence is likely and becomes very frustrating for the patient.

PRP is very successful at replacing this unhealthy tissue with healthy tissue and restoring function and allowing a return to normal physical activities. PRP offers no quick pain relief and has no pain-relieving properties. The pain gradually subsides as the injured tissue repairs itself. This can take weeks or months, but when successful, the effect is lasting. Most patients will need 2-3 treatments spaced about 4 weeks apart and most people will not feel any relief until a few weeks after the second treatment and that relief is gradual and sometimes like a roller coaster ride in that there will often be a few pain-free days mixed in with a day or so of resolving soreness.

There are three populations of patients that benefit from PRP. First are those with chronic pain from tendon or ligament dysfunction such as Achilles tendinopathy in runners. The second group is those patients with acute injuries such as a tennis player with a muscle tear, and finally, it has been shown that PRP is effective in treating osteoarthritis.

PRP is an acceleration of the body’s own healing process and thereby is a purely natural process so there is no risk of allergic reaction or reaction. The patient is not being given anything that doesn’t belong to them. Infection is very unlikely as platelets by nature are anti-infective which why it is very unusual to develop an infection when you fall and skin your knee. The only drug that is used is the local anesthetic to numb the area prior to receiving the PRP treatment.

At Beacon, all treatments are done under ultrasound-guided needle placement to ensure precise placement of the PRP at the injured site and ensure the needle is not going where it should not such as uninjured tissue, nerve, or blood vessels.

The success rate for Dr. Stiene’s patients is well over 80% in terms of a full return to their desired level of physical, athletic, and recreational activities. Beacon Orthopaedics maintains electronic medical records (EMR) that allow data to be tracked and outcomes measured.
Over the last number of years, much has been learned about PRP in terms of the timing of the injections, the frequency of the injections and the concentration of the platelets that are used to treat injury or osteoarthritis. Dr. Stiene and have his staff have learned how to vary the concentration of PRP to suit the individual patient. This includes the removal of white blood cells. White blood cells are currently thought to be responsible for a good portion of the post-procedure pain. It has also been found that the use of Prolotherapy in conjunction with PRP can provide optimal outcomes. Dr. Stiene and his staff are the only medical providers in the Tri-State area licensed to perform Regenexx procedures which include mesenchymal stem cell therapy, injection of growth factors derived from PRP and modifying the concentration of PRP.

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